How Do Stat6 Inhibitors Work in Immune Regulation?
These inhibitors are of high importance as a number of the signaling pathways involved in immune responses have been implicated to use STAT6, which is essential for them. STAT6 protein is mainly phosphorylated by interleukin-4 (IL-4) and IL-13, which are essential in the differentiation of T-helper 2(Th2) cells. Th2 cells help regulate allergic responses; the …
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